The new SlideCollector 48 for the PALM Microbeam and PALM CombiSystem is now available from Carl Zeiss. The SlideCollector 48 enables the seamless integration of noncontact Laser Capture Microdissection (LCM) and single-cell AmpliGrid assay technology into one continuous, automated workflow. This ensures the highest levels of sample purity for applications in immunobiology, genetics, cancer research, stem cell research and forensics. In addition, the 1 microlitre assay cells minimise reagent costs, enabling a wide variety of single cell analyses. Because single cells can be easily harvested without contaminating tissue, conventional cell pooling steps are unnecessary.