Shimadzu has updated its line of AXIMA MALDI TOF mass spectrometers (MS) with three new systems to meet the needs of researchers with varying applications and budgets. The AXIMA Performance mass spectrometer provides the pinnacle of performance for high-energy MS/MS interrogation of proteomics, biological and organic samples. These include peptides, polymers, oligonucleotides, SNPs, metabolites and carbohydrates. Shimadzu designed the AXIMA Confidence and Assurance instruments with general analytical and life-science laboratories in mind. Both systems are affordable, robust options for routine sample analysis performed manually or automatically. Positive- and negative-ion modes are standard, allowing users full flexibility.