New 4titude FRAMEstar PCR plates, now available from Anachem have a novel two-component design that combines the advantages of a rigid skirt and deck for reliable robotic handling together with thin-walled wells for optimum PCR results. The wells are constructed from virgin polypropylene, providing the most efficient heat transfer, along with an inert surface with low binding capabilities for nucleic acids, proteins and other molecules. 4titude provides superior products for rapid PCR and small reaction volumes by utilising novel injection moulding technology, enabling the wall thickness to be reduced without compromising on tube integrity. In comparison with the traditional single piece products, the mechanical stability of the plate is greatly improved by moulding the plate frame in polycarbonate.