Applied Biosystems has introduced an 8plex version to its line of iTRAQ labelling reagents, to double the existing capacity for biomarker discovery and comparing protein levels between samples. The increased capacity of the new iTRAQ reagents enables researchers to obtain higher throughput and greater efficiency than label-free methods or other approaches with limited multiplexing capacity, so experiments that might otherwise take months can be completed, with better accuracy, in a matter of days or weeks. With the introduction of 8plex reagents, researchers can efficiently expand their quantitiative proteomic experiments by simultaneously analysing eight samples in a single experiment. The new reagents should make the process of biomarker discovery more productive by increasing the scale of experiments conducted.