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 Beckman Coulter UK has introduced the gTox Flow Kit – a new flow-cytometric approach to genotoxicity testing. This mouse micronuclei assay is designed to evaluate the ability
of a compound to cause chromosomal damage. It detects micronuclei formed from chromatin that are displaced as result of chromosomal breakage. These nuclei are formed outside the main nucleus of the dividing cell. The gTox Flow assay enumerates micronucleated red cells in peripheral blood of treated mice. It is ideal for preclinical drug candidate testing,
environmental testing and other academic and commercial toxicology applications. It is also one of a battery of tests that chemical companies can use to comply with stringent new REACH (registration, evaluation, authorisation and restriction of chemical substances) regulations in Europe.
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